Recently, a group of researchers from Singapore analyzed the effects of green tea extract gallate -3- gallate (EGCG) on mice and published the results in the Journal of molecular nutrition and food research. The researchers say that too much fat in the diet can lead to overweight, obesity, and overnutrition, and it also affects brain function and sends signals that continue to eat.
Although many previous studies have found that green tea extracts, such as EGCG, have the effect of preventing obesity, many of them study the relationship between green tea and human metabolism, and few studies have focused on the relationship between green tea and the central nervous system and dietary behavior, the researchers say.
In this study, the researchers chose a number of male wild mice, which were randomly divided into three groups, feeding a group of regular foods and feeding the first two groups of high fat food for a week, with 60% of the energy, and feeding third groups of high fat foods for three months. In addition, all mice were fed with EGGC supplements.
The results showed that EGGC had no significant effect on the conventional food group, but in the high fat diet group, the two groups of rats had improved their eating habits and reduced food intake and feeding frequency. EGCG supplements can prevent high fat diet (HFD) mice from overeating during the day, that is, EGCG can regulate diet behavior and energy homeostasis in rats.
In addition, the researchers found that EGCG regulates the expression of key appetite management genes, such as AGRP, POMC, and CART, and also affects the gene physiological clock in the hypothalamus of obese mice, which all show the regulatory effect of EGCG on mice.